Cannabis Extracts Maintenance Guide

This guide is intended to assist you with storage, handling, dosing, and scheduling of your Constance Therapeutics products. Please read this guide thoroughly before using the products, and regarding any questions or concerns you may have, please contact the staff at Constance Therapeutics.

This guide was specifically designed for your use and application of cannabis extracts obtained through Constance Therapeutics pursuant to the medicinal cannabis laws of the State of California. Do not use this guide with any other cannabis oils, concentrates, or cannabis-related products from distributors of other products.

Disclaimer: Constance Therapeutics and its staff are prohibited from making any medical claims that these products can or may treat, cure, or prevent any disease including, but not limited to, cancer. Constance Therapeutics and its staff are not licensed physicians or medical or healthcare providers. This guide and its instructions do not and are not intended to constitute or act as a substitute for professional medical advice or medical guidance. Please consult with your physician or healthcare provider before use of these products. The following statements and instructions in this guide have not been evaluated or approved by the United States Food and Drug Administration. Constance Therapeutics and its staff make no healing, curative or medical claims or warranties regarding its products.


Store the extract away from light and heat. We advise keeping the extract in a cupboard or drawer at room temperature, away from excessive heat or cold. Do not allow the extract to reach temperatures of 102°F (this will not destroy the product but the quality of the extract may become compromised). Make sure to keep the extract away from children and pets.


Here is a step-by-step guide to dispensing the extract:

  1. Lightly shake before use.
  2. Remove childproof cap from glass bottle by pushing down and turning counterclockwise simultaneously.
  3. Insert the syringe tip fully into opening of the glass bottle. Note: There is no need to force the syringe deep into the opening. This may cause the plastic plug in the bottle to split and cause leakage. Instead, gently press just the narrow tip of the syringe into the plug so that it forms a seal between the syringe and the plastic plug.
  4. Turn bottle upside down with syringe inserted.
  5. Slowly retract then push the plunger to remove any air bubbles from syringe. Withdraw plunger to the desired dose. Refer to the dosing schedule below.
  6. Dispense the extract directly under the tongue into the mouth, and allow to rest under your tongue for up to 2 minutes before swallowing. You may take with food or drink, and it is advised not to take on an empty stomach.

We do NOT recommend using suppositories as an alternative method. Please consult with us before deciding to change your administration method of the extract, and consult with your physician or healthcare provider regarding the same.

We do not have any offcial recommendations for diet or nutrition while taking the extract; however, it may be helpful to take the extract with healthy fats, such as coconut oil or avocado as they can enhance cannabinoid absorption. Ultimately, you will need to consult with your physician or healthcare provider regarding your diet and/or nutrition while on the extract.

Dosing Schedule

All dosing should be done in consultation with your treating physician or healthcare provider. Our recommendation based on past patient experiences is to ingest the extract at night about two hours before you go to sleep and to adjust the time as you adapt to cannabis extract and learn your own body’s response to it.

For those that have taken and completed the 39k Protocol, the recommended Maintenance dose is 0.6mL of the cannabis extract a day. If you are new to the extracts and have not taken the 39k Protocol, you will be building up to 0.6mL of the cannabis extract a day. We advise you to stay there indefinitely or as directed by your physician or healthcare provider.

The following schedule is meant as a guideline and should be visited with your physician or healthcare provider. Please try to stick to this schedule as best as you can. If you need to significantly alter the schedule, contact us so we may advise you and also contact your physician or healthcare provider regarding the same, if helpful and desired.

Recommended Dosing Guide

Recommended dosing schedule for our cannabis extract diluted in sunflower oil, taken at night, approximately 2 hours before bed:


*Note that the recommended Maintenance dose for those coming off of the 39k Protocol is 0.6mL or 60mg of the cannabis extract a day.


Side Effects

Higher THC Extracts: If taken before bed, the majority of the psychoactive side effects of THC will happen while you are asleep. If you start to feel uncomfortable side effects, the best thing to do is remain calm and go to sleep. Remember that the cannabis will not hurt you and the effects will subside with time. Common side effects include short-term memory impairment, disorientation, dry mouth, time distortion, dizziness, anxiety/panic attacks, drowsiness, and a ‘high/strange’ feeling. These can wear off quickly or continue throughout the day. Your body will slowly acclimate to the effects of THC and it will become easier as you continue, according to our patient members.

If you experience something that is out of the range of common side effects, please consult your physician. We are not physicians or trained healthcare professionals, but are always happy to provide our specialized knowledge of cannabis extracts.

Frequently Asked Questions


Q: Can I stop taking my other medications if the cannabis extracts help me?

A: We do not recommend doing anything without first consulting your physician or healthcare provider in regards to your other medications. Constance Therapeutics and its staff are not licensed physicians or medical or healthcare providers.

Q: Can I drive?

A: This is within your sole discretion. Please do not drive if you do not feel like you can't.

Q: Can I work?

A: Maintenance should allow you to resume your regular daily life. Working is within your sole discretion. If you want to give your body the best chance of healing, we encourage you to rest when you feel like resting. Consult your physician or healthcare provider accordingly.

Q: Can I take a day off from Maintenance?

A: Unless your physician or healthcare provider advises you to abstain from continuing on Maintenance, we do NOT recommend discontinuing your Maintenance dose. This is a small amount of extract to be taken daily or frequently in order to keep the cannabinoids present in your fat cells. You can either persist with the recommended daily dose, or you might shift to taking a relative weekly dose amount every-other-day or broken up throughout your week. Again, be sure to consult your physician or healthcare provider accordingly.

Constance Finley